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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8d4503e4d1c2981bcd4983eda187c49428b95f5f16b0e4efa4f3ef951c6e358f' 
  AND token = 'QIIz1n7dIyzT3A2n8S5XXJnSQuBhVbBfNYsZU2Yzsas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}