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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '15f4f2bb8faa5f8f7d81d4eb254ebb44b72c184f80854abfd5c33fadb50695fb' 
  AND token = '4Z9nP9Ya3VPd5nqVa9mpb+y8W1OPxQUQJsQSLlk5jlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}