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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4257146f6e9ecbce6a343666981accaeec0aa54e577bba72ddfa1ca9d62b83fb' 
  AND token = 'dEICQ9M8vE2AWMPg6GjcH7j2bK3wFS2oZ/ZtSNt/18A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}