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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '18d4b6d5e9e3a6909068b303899fdf76ce9ead2dcc6116d0a49b93613eba013d' 
  AND token = '39iFuAP4fuKNMW4JReDqJLkWn3EZ/qGt0No9hkfEnjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}