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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'afce28a698d1d8ccad72859a09ba37242adc8a0d5739722709ccf582d5d818b6' 
  AND token = 'UHG0jGCgJHAafl+xNPp0uWq5jHn3B1WoShDjR11AYEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}