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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1e32efb4595b9d35c5719e12738b1c2d5648320101f161667e5c3fa59e90b337' 
  AND token = '9fpoJR8NBMrLyffDDa99pf9BBesIW/WaKXwDApS/Hlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}