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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1278bc5fdc401f40432ab18111eeb1da306823bdde1282ee1f900f0aed904827' 
  AND token = 'a69v36XQTzd7ob0WKN09rTGxXLlGjemYEPAGLdtwDUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}