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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ad6bb5d1544a6f612c7f2f487511d74300f8df97e9d821c13ac47f2397e3efc' 
  AND token = 'mvv8dxdBm0gceK56BF944PXlgb9rKKh91R6wWzysFW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}