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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '96b54f76f460dff65785cdd55a0f1f41f95080fe9f251c40836ff29ae366fe37' 
  AND token = 'NQDxD239SJ7p+lm8qhqlN31sYAsKnGnYY8wQ6Yh7HrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}