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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fff3ce1fc8293cced2ef426c969b1485c3756afa258bc5f1cf89c3489e962915' 
  AND token = 'T4dj4y8kMa5FDObYuL5SDib3T/+0wgmZA+KZYkg0WY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}