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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '01a3052eb58cf3769b35612a8f8d9cc9d66b55af2666c8b07a7f2256be5545c6' 
  AND token = 'agTynSrS4s8hrBDAh6n+NiPl2HT+ywt2Mrp4cMOjHFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}