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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8364d66c34ee889d000484bb52337b620b8b56f030d33e36fb82f0095705e6b0' 
  AND token = 'uAk1rXWcUntRiw2bYEb1j8RiACGzXp5zBg47lEZty2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}