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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e88cfe626d7bae803c52d529adb894a1db32924d5d645e7a93553f4437007178' 
  AND token = 'TcFI0jtnA8dNZuz8l5OXwyFcC8wlC9tGikbMztxU894=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}