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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '75ec3bf23ac60ed7e8bf710d0e4cb5565adb3232b92912c1f86449b909403c24' 
  AND token = 'P4ReJmhKtt+xPUWxsndwobWTyF4KIU0ad/WcCiiDfdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}