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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'df49c9c3422cbd79ec89b8d48c3991a6c7b83e24e8fd3e641de285b170b9e5fb' 
  AND token = 'gpf49/XFGx6BVxJqT8O/f3nAxFofXcI3HKCsVWY3SbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}