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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65688242b8ad263561d11a924670bcea3fd2d2fcc35be466d94c769a09ec68cc' 
  AND token = 'kUM8DAd5Vd3R4xyt0T2ez+H0ETl5xIL12MJzmb3wik8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}