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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9619228ca9042904d72947ea9273c2c413a0ba66126ddc2424789a34292777b6' 
  AND token = 'kUqbF0uVu1P5VzfhAO0JC1JoV+WU/JpNtMvsW1ESfA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}