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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5281fad29ac695ad2eac32cd14e94cfed7ffd51639db40fe9f41729220e63b5d' 
  AND token = 'sSx1rXqqbbfStRWF9OytG3qhOjulSkR9DUPIO5QDiQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}