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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5fbe81c3cf9269b08eaa58396c586dbc1ad5dde7da23abc9d4b31681b01a0845' 
  AND token = 'ocyJziyXWrPgHdOlWSyoCLHVDj+y5wJlL+IpMN+UbFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}