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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '649e6f5a0342f90f33a1d8bd30c37e1d09efbd16c568db467fb9dc92988ade4e' 
  AND token = 'TdNtcT1nCL4ysXV9BUy6oWoUP9PPfmd996qua2p38dA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}