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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c5a558a8cc8ef5780e10744213d33d3dba6c0529a7349881bb662a88d36eb82' 
  AND token = 'yAaaQZoJpjKnt8CQI3FTIi4ST9LGxtsI3nM2LqN7nEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}