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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21f218d722a5b70f14c83ca88e0004ec8913da26a3756fa0d3bbceda3882b8ca' 
  AND token = '49xppEcPQATXTUOEPgcx3cEeRkYCuUDAyNVtqLb7Q5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}