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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5f22c79480804d147a994ae54bad7a46397b0fc85cd0110572b71b106a86dbf5' 
  AND token = 'KOtN/AcuxNR3EJXEFL7g9gIfbF9HB6pQGPu9gXD75nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}