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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e2c3f0a727e4e28e44520c6065cf140bdfdd5620f072c9e2ee9df921b8703114' 
  AND token = 'Vn6dr09SqYrCkKX65lTHoWp3eFeIdhBWDCDEFZUfsls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}