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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b43b351a908f29559ff48cd9c239c539870f6c8a47f538b9e5e635e80d83c4e7' 
  AND token = 'eMXnspDZAz2fnrX/qpqOUV/JmsiIuxpAiNil6tRMxC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}