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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78b0d5c582910e71dcdd77a50bf79d20bd52c74ec6715cc8ca8352a08f7341f4' 
  AND token = 'uwvAS32lr7vavwehbSENmFv/n06ii/EGZ64+taSmfcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}