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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9b6e7c3de2e4cf3c29912f3825e095014cce208b1f17977cb4e25f5fd6005bbf' 
  AND token = 'IPQkp0ueT3xb0UAZi2440bp1GqCAW11JwJvn/7CeEsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}