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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '72877d405e0aff4174d4fdc72bf3ced54496163770ef600ff3fdfda421cdad05' 
  AND token = 'FFm6Wv53sIByqZdkR97iul7X1yhwwFilRIf9Vo0cU50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}