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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '39ce8c299fe46a0f5765055099d2db5dc1f27655074eb020d999fa1243c073f2' 
  AND token = '+4PsPG7SxrVqPJHzO0gCUrHcossUMAay9m+bPxX51xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}