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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cb5cf727bfaecc2792a3950730db1a4face2d8e5440030ca4e44af5c5d442004' 
  AND token = '4qypiCw7RlYwyGgKRQQa1GdkRCiX/9bbf6lH40WYREM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}