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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0f8853f5a371793bd13ae07a0caca9615d74e5acf15c06284609785d6264418e' 
  AND token = 'HiR3FpzdGOSkIbdgZngZYyMOnxNp3lUfrXZ4lgvkZQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}