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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd88ce2f05b90a0490e616a20f03ce5a233c32a4720b8188c5ca145145e9426a2' 
  AND token = '4PzjV3nV6h7RIyNL6dcGaDGHhzxj54Zw1UtPf1MniUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}