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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c5cee6638a956ef70122b6be87f1b99ba0d4e7c0b45b14c1d10b70d586c21720' 
  AND token = 'XOewNlp5k5x3omRf6bKdi9Q3QIUYAN1pEZSBeRlhnAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}