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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45fb3daa406236c088985d3722c3f7ba2e2acefac471d4c3dc84b8d384ea7295' 
  AND token = '4l1FIWsLumrduko69N0l+948gWDiO6t52KEW5VNhUms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}