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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '12be01ddd78964d31ed5e44918560a9e44bf4b009907d6672070b0c0d0d4cd37' 
  AND token = '5E8ZOjYbfGWEXpbp9zbGG+szcCkI7FyxkI1aUpDVHNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}