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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4381697901d44a3755c43f60e6d02d25054199d175c26bc1be2db090f97c583b' 
  AND token = '88pW1y59sUCYbnONxzGSZP4nvaisSqYs68sGjQ4CkqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}