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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '421bd2c48a424c4e4614938406e68f307d24e0fdb28267656e74620239afb241' 
  AND token = 'rZRyiVKKHLFoMpP5t7fi3CSNDpUSHPIpak/Wr0qkgKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}