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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0721c24abfb0196a18d55eb8f64c5e28521c25c8b350b0653e0eb5ba8bf46b6e' 
  AND token = '+RFtSvFie6Eg9G57cgyTKNBIOF3STdty0FUlUlU8yiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}