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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '38ffb5951a8f12252af35d35fc3332b2af3be1708dec90ccbada97c7960c1d4b' 
  AND token = 'LH2nq3SMFC3aKPtIND0MHCNpO5uZX4HlVVh6gW+sAE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}