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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0e0338c72289001dc76b768c24520c4b64f08a9ee006ebda26b928bfe06e1cf6' 
  AND token = 'rEBKH2r6hhXS9P6+0xset31na4qu7bR2bMO/JvUIgS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}