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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '624250c2ec36db49bebb70a20aaa79bb89b3eda8c06d473bf7490564d9a9f1f0' 
  AND token = 'Q54xCcWuGxJjyJQYcjI7yjaAKqwyY/+sqdEnMGaeD3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}