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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '73529a281e8bb53f27f4e6f5c771536377b048adb6a11c9cc9562ae4e31acd99' 
  AND token = '/4aSpQ8dcFGEM6Z8j0r4bIsWoEh2VUXWMW48xKfoRI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}