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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f880e5cff8c2220e960d79a63af6b2d1dd35bf976fccdb168afd8b2a72993642' 
  AND token = 'by3sy8lATmxJVF3pJ8GbvPUjOvYd9eRvWjI/frMILPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}