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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a5df378c6d58eb458aa02a47a80a2b3ab66a2b531cb3748e15c85d3726ad71b8' 
  AND token = 'M6M/F2hTKzHxVPfKYgVeONhtWcJly2AeqgTHHI7Jbzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}