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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7416ae7aa3c2c72886fd46030182a0e001a7381c8eb1d65cfd35d2c39fe102b0' 
  AND token = 'ANw1vrOL4P7WVWQ8oAV+Zy4p3bM6kmJmJcmaLN92ID8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}