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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b9d20d0220d3745af07ae2fbbdcea3b6fb121d9cd42134e1ed040e2db012f427' 
  AND token = 'pOzniQixhD4Th/zeIsz+s3vRpZp0n6IaFgjWcxNDhK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}