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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3780953410257ce9e22fdda3400b8db2740374e51f51bb21b259e9c119a4d950' 
  AND token = 'rw02iYeFDbRocjjrFLNfXRRjyxA+b9Ks9wI3Zf/7d0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}