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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9778269510955315b40bd85ebb6ff63dbbca6599ab22ea3c843d6ed26feee0a4' 
  AND token = 'WPTT3Kle5BMUI4rnKQH4C3fCK8ePhb7bAIPN3mcmNwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}