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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '648399d8ff6a3f164dfdcf08dc3b5775264e9d4b1be534fb52f11387564e5ecc' 
  AND token = 'dyImYdmj24K0lbRTnlAcxqqkj52f5d1H6EQDsL9KNH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}