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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '653f8c48e843ec49e2b08edae952ae35d2564239f040b8a238ac111a15017345' 
  AND token = 'lYMTw8SiOyDj2BIbRcOhbYR1IHFLR65W85TazGeZ2kw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}